Determination of Isoniazid by Fe(II)-2,2’-Bipyridine Spectrophotometry
نویسندگان
چکیده
In acidic media, Fe(Ш) could be reduced to Fe(Ⅱ) by isoniazid, reacts with 2,2'-bipyridine form an orange complex a maximum absorption wavelength of 522 nm. According this principle, the content isoniazid can measured indirectly measuring amount Fe(Ⅱ). A new method for determination Fe(Ⅱ)-2,2'-bipyridine spectrophotometry has been established. At optimum conditions, linear relationship is good between mass concentration and absorbance in range 0.0004000-0.002800 mg/mL. The regression equation A=0.0251+138.04C(mg/mL), correlation coefficient 0.9995. This used determine tablets, results are similar those obtained pharmacopoeia method.
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ژورنال
عنوان ژورنال: E3S web of conferences
سال: 2021
ISSN: ['2555-0403', '2267-1242']
DOI: https://doi.org/10.1051/e3sconf/202129001028